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- Topp KS, Faddis BT, Vijayan VK. Trauma-induced proliferation of astrocytes within the brains of young and aged rats.
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- Alonso G, Privat A. Reactive astrocytes involved within the formation of lesional scars differ within the mediobasal hypothalamus and in different forebrain regions.
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After a penetrating lesion in the central nervous system, astrocytes enlarge, divide, and take part in creating an surroundings that adversely impacts neuronal regeneration. We have lately proven that the neural cell adhesion molecule (N-CAM) partially inhibits the division of early postnatal rat astrocytes in vitro. Animals have been lesioned in the cerebral cortex, hippocampus, or striatum with a Hamilton syringe and needle at outlined stereotaxic positions. On one side, the lesions have been concomitantly infused with N-CAM or with one of the N-CAM-related molecules. As a control, a peptide of the identical composition because the N-CAM decapeptide but of random sequence was infused on the contralateral aspect of the mind. The inhibition was best within the cortical lesion sites (approximately 50%) and was less pronounced in the hippocampus (approximately 25%) and striatum (approximately 20%). Two weeks after the lesion, the cerebral cortical sites infused with N-CAM continued to exhibit a considerably smaller population of dividing astrocytes than the sites on the alternative facet.
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Hemperly JJ, Murray BA, Edelman GM, Cunningham BA. Sequence of a cDNA clone encoding the polysialic acid-rich and cytoplasmic domains of the neural cell adhesion molecule N-CAM. Hunter KE, Ssex MB, Davies AM. Transforming progress factor-betas inhibit mitogen-stimulated proliferation of astrocytes. Barrett CP, Donati EJ, Guth L. Differences between adult and neonatal rats of their astroglial response to spinal harm. This will not be the entire listing of references from this text. Federal authorities websites often end in .gov or .mil. Before sharing sensitive data, ensure you’re on a federal authorities site. These are some of the greatest Omegle different websites.
